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|Title:||Discriminating Astragali Radix from its adulterants using HPLC coupled with chemometric clustering techniques|
Principle component analysis
Hierarchical cluster analysis
|Publisher:||Food and Drug Administration, Department of Health, Executive Yuan|
|Source:||Journal of food and drug analysis, 2011, v. 19, no. 4, p. 495-501.|
|Abstract:||A simple high-performance liquid chromatography (HPLC) method coupled with principal component analysis (PCA) and hierarchical cluster analysis (HCA) was developed for distinguishing Astragali Radix from its adulterants. Five species, including A. membranaceus var. mongolicus, A. membranaceus, H. polybotrys, A. chrysopterus and A. ernestii, were analyzed by this method. At the same time, four major bioactive isoflavonoids, namely calycosin-7-O-D-glucopyranoside, ononin, calycosin and formononetin, were simultaneously determined in Astragali Radix. This method was proven to have good precision, repeatability, stability and recovery. It was successfully applied to distinguish Astragali Radix from its adulterants species and can be used for the quality control of Astragali Radix.|
|Rights:||Copyright 2012, FDA. All Rights Reserved.|
Posted with permission of the publisher.
|Appears in Collections:||ABCT Journal/Magazine Articles|
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