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Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/5295

Title: Discriminating Astragali Radix from its adulterants using HPLC coupled with chemometric clustering techniques
Authors: Dong, Wei-Wei
Au, Dawn
Cao, Xin-Wei
Li, Xiao-Bo
Yang, Dajian
Subjects: Astragali Radix
Isoflavonoids
HPLC
Principle component analysis
Hierarchical cluster analysis
Issue Date: 2011
Publisher: Food and Drug Administration, Department of Health, Executive Yuan
Citation: Journal of food and drug analysis, 2011, v. 19, no. 4, p. 495-501.
Abstract: A simple high-performance liquid chromatography (HPLC) method coupled with principal component analysis (PCA) and hierarchical cluster analysis (HCA) was developed for distinguishing Astragali Radix from its adulterants. Five species, including A. membranaceus var. mongolicus, A. membranaceus, H. polybotrys, A. chrysopterus and A. ernestii, were analyzed by this method. At the same time, four major bioactive isoflavonoids, namely calycosin-7-O-D-glucopyranoside, ononin, calycosin and formononetin, were simultaneously determined in Astragali Radix. This method was proven to have good precision, repeatability, stability and recovery. It was successfully applied to distinguish Astragali Radix from its adulterants species and can be used for the quality control of Astragali Radix.
Rights: Copyright 2012, FDA. All Rights Reserved.
Posted with permission of the publisher.
Type: Journal/Magazine Article
URI: http://hdl.handle.net/10397/5295
ISSN: 1021-9498
Appears in Collections:ABCT Journal/Magazine Articles

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