PolyU IR Collection: ABCT Patents http://hdl.handle.net/10397/44 The Collection's search engine Search the Channel search http://repository.lib.polyu.edu.hk/jspui/simple-search Ligands for transition-metals and methods of use http://hdl.handle.net/10397/5227 Title: Ligands for transition-metals and methods of use<br/><br/>Authors: Kwong, Fuk Yee; So, Chau Ming<br/><br/>Abstract: The present invention relates to indolyl phosphine ligands, and methods of making such ligands utilizing phenyl hydrazines and aryl ketones as the starting material. The present invention further includes uses of the ligands in the synthesis of pharmaceuticals, materials, and agriculture. Method for separating catechin from green tea = 从绿茶茶叶分离儿茶素的方法 http://hdl.handle.net/10397/4896 Title: Method for separating catechin from green tea = 从绿茶茶叶分离儿茶素的方法<br/><br/>Authors: Chan, Tak-hang (陳德恆); Lam, Wai-har (林惠霞)<br/><br/>Abstract: The invention relates to prodrugs of 8-ss-substituted estratrienes of general formula (I) in which the Z group is bonded to the steroid, method for production thereof, pharmaceutical compositions comprising said compounds and use thereof. Said compounds of general formula (I) do not bind to a- and/or ss- estrogen receptors, but to carboanhydrases and inhibit said enzymes.; 已有许多关于从绿茶分离(-)-EGCG的报道。然而，许多水溶性与 儿茶素相似并且结构与儿茶素类似的组分的存在使得分离纯(-)-EGCG 变得困难。缺少简单、有效和廉价的获得纯(-)-EGCG的方法妨碍了在 动物和人的临床研究中对(-)-EGCG进行评估。本发明提供了分离儿茶 素(包括(-)-EGCG)的方法：首先将儿茶素转化成它们各自的酯形式，然 后通过色谱法分离酯化的儿茶素，并将其变回到儿茶素。本发明的方 法相对简单，并且可获得大量的儿茶素。 Polyphenol proteasome inhibitors, synthesis, and methods of use http://hdl.handle.net/10397/4848 Title: Polyphenol proteasome inhibitors, synthesis, and methods of use<br/><br/>Authors: Dou, Q. Ping; Chan, Tak-hang; Smith, David M.<br/><br/>Abstract: The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers. Method of biosynthesizing tetrodotoxin http://hdl.handle.net/10397/4590 Title: Method of biosynthesizing tetrodotoxin<br/><br/>Authors: Yu, Peter H.; Yu, Chun-fai<br/><br/>Abstract: The present invention relates methods for the biosynthesis of tetrodotoxin (TTX) involving the steps of obtaining a culture possessing one or more of a Vibrio species, such as through a seed culture, inoculating the culture and tissue extract from a textrodotoxin-bearing organism in a fermenter medium, and isolating and purifying tetrodotoxin from said fermenter, resulting in a yield of TTX of about 0.5 g TTX/L in about 3 to 5 days, such TTX being at least 90% pure.